Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477818 | 0.82 | TSHR (0.42) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4849392 | 0.81 | TSHR (0.51) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4959311 | 0.81 | TSHR (0.51) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4395957 | 0.80 | TSHR (0.50) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19873254 | 0.80 | TSHR (0.58) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14562274 | 0.80 | TSHR (0.48) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL6154976 | 0.79 | TSHR (0.49) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7516232 | 0.78 | TSHR (0.46) | TSHRHSD17B10KDM4ESMN1; SMN2TP53 | |
| SCHEMBL4844621 | 0.77 | KDM4E (0.70) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4850809 | 0.77 | KDM4E (0.50) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781767-B1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5981749-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5795984-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-08-18 | — | — | US | disclosed |