Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555013 | 0.94 | KDM4E (0.49) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4849392 | 0.90 | TSHR (0.51) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL6879560 | 0.86 | TDP1 (0.47) | TSHRHSD17B10KDM4ENCOA1NCOA3 | |
| SCHEMBL14373029 | 0.84 | TSHR (0.49) | TSHRHSD17B10KDM4ENCOA1NCOA3 | |
| SCHEMBL4959311 | 0.80 | TSHR (0.51) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL10697777 | 0.80 | KDM4E (0.48) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL27793485 | 0.79 | KDM4E (0.50) | HSD17B10KDM4ESMN1; SMN2LMNATP53 | |
| SCHEMBL4410409 | 0.79 | TSHR (0.45) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7781045 | 0.79 | TSHR (0.50) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19873254 | 0.79 | TSHR (0.58) | TSHRHSD17B10KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |