Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 11/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.57 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.57 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL7781258 | 1.00 | GRIK1 (0.57) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL135731 | 1.00 | GRIK1 (0.57) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL28302585 | 0.90 | SLC7A5 (0.52) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL11269603 | 0.90 | GRIK1 (0.54) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL7782858 | 0.90 | GRIK1 (0.54) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL27469897 | 0.90 | SLC7A5 (0.52) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL7204819 | 0.90 | SLC7A5 (0.56) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL8383423 | 0.90 | SLC7A5 (0.56) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL28054217 | 0.90 | SLC7A5 (0.56) | GRIK1GRIA4GRIK3GRIK5SLC7A5 | |
| Aspartic Acid SCHEMBL7204816 | 0.90 | SLC7A5 (0.56) | GRIK1GRIA4GRIK3GRIK5SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723194-B1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK CO (US) | 2001-09-26 | — | — | EP | claimed |
| US-5582958-A | USEFUL IN REHALOGENATING FERRIC CHELATE BLEACHES | EASTMAN KODAK COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| EP-0723194-A1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK COMPANY (US) | 1996-07-24 | — | — | EP | claimed |
| US-5521056-A | BIODEGRADATION | EASTMAN KODAK COMPANY (US) | 1996-05-28 | — | — | US | claimed |
| EP-0723194-B1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK CO (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6096487-A | CYAN DYE DENSITY MAXIMIZED IN COLOR DEVELOPED SILVER HALIDE PHOTOGRAPHIC COLOR MATERIALS BY USING A MIXTURE OF A FERRIC COMPLEX OF SPECIFIED AMINOPOLYCARBOXYLIC ACIDS AND UNCOMPLEXED PYRIDINECARBOXYLIC ACID(S) IN GIVEN MOLAR RATIO | EASTMAN KODAK COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0859276-A1 | Cyan dye recovery using ferric aminopolycarboxylic acid bleaching composition | EASTMAN KODAK COMPANY (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5753423-A | ACID SOLUTIONS OF SUCCINIC ACID, MALEIC ACID OR MALIC ACID WITH AMINOPOLYCARBOXYLIC AID, MIXING FERRIC ION, ADDING BASE TO CHANGE PH | EASTMAN KODAK COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5582958-A | USEFUL IN REHALOGENATING FERRIC CHELATE BLEACHES | EASTMAN KODAK COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0723194-A1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5521056-A | BIODEGRADATION | EASTMAN KODAK COMPANY (US) | 1996-05-28 | — | — | US | disclosed |