SCHEMBL7781591

SCHEMBL7781591

CCCCC[C@H]1CO[C@H](CC[C@H]2CO[C@H](c3cc(F)c(F)c(F)c3)OC2)OC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7781594 1.00 ALDH1A1 (0.33) ALDH1A1CYP1A2
SCHEMBL7781372 0.99 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7781373 0.99 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7779293 0.96
SCHEMBL7779290 0.96
SCHEMBL7781529 0.93 ALDH1A1 (0.33) ALDH1A1
SCHEMBL7781536 0.93 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9503692 0.93 ALDH1A1 (0.37) ALDH1A1CYP1A2
SCHEMBL9763985 0.92 ALDH1A1 (0.40) ALDH1A1CYP1A2
SCHEMBL9764036 0.92 ALDH1A1 (0.40) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732330-B1 Di-1,3-dioxane derivatives useful as liquid crystals ROLIC AG (CH) 2001-09-12 EP disclosed
US-5667721-A Liquid crystalline di-1,3-dioxane derivatives ROLIC AG (CH) 1997-09-16 US disclosed
EP-0732330-A1 Di-1,3-dioxane derivatives useful as liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1996-09-18 EP disclosed