Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.61 |
| ▸ | TYMP | P19971 | 5/20 | 0.58 |
| ▸ | PYGM | P11217 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160426 | 0.89 | LMNA (0.52) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5983808 | 0.89 | LMNA (0.52) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL10895353 | 0.88 | LMNA (0.56) | TK2TYMPPYGMLMNA | |
| SCHEMBL9556674 | 0.88 | TK2 (0.57) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL24263988 | 0.87 | TK2 (0.58) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL15691446 | 0.87 | TK2 (0.58) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL19132641 | 0.87 | TK2 (0.58) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL15691496 | 0.87 | TK2 (0.58) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL30528760 | 0.87 | TK2 (0.58) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL20636931 | 0.86 | TK2 (0.56) | TK2TYMPPYGMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816570-A | Biologically reversible phosphate and phosphonate protective groups | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-03-28 | — | — | US | claimed |
| EP-2262820-B1 | METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS | UNIV HAMBURG (DE) | 2013-06-19 | — | — | EP | disclosed |
| EP-0707591-B1 | METHYLPHOSPHONIC ACID ESTER, PROCESS FOR PREPARING THE SAME AND ITS USE | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0707591-A1 | METHYLPHOSPHONIC ACID ESTER, PROCESS FOR PREPARING THE SAME AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001363-A1 | METHYLPHOSPHONIC ACID ESTER, PROCESS FOR PREPARING THE SAME AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |