⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858922 | 1.00 | — | — | |
| SCHEMBL8791174 | 0.87 | ELANE (0.30) | — | |
| SCHEMBL8791183 | 0.87 | ELANE (0.30) | — | |
| SCHEMBL8622545 | 0.87 | ELANE (0.30) | — | |
| SCHEMBL8858920 | 0.84 | — | — | |
| SCHEMBL7783236 | 0.84 | — | — | |
| SCHEMBL3804896 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL7776403 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL7776405 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL14580526 | 0.83 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0635488-A2 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |