Tryptophan

Tryptophan

SCHEMBL7781895

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.[K]

nearest known ligand 0.97

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.97
KDM4E B2RXH2 3/20 0.97
MAPT P10636 3/20 0.97
LMNA P02545 2/20 0.97
TSHR P16473 2/20 0.97
BLM P54132 2/20 0.97
PMP22 Q01453 2/20 0.97
MEN1 O00255 2/20 0.97
MPO P05164 1/20 0.97
HIF1A Q16665 1/20 0.97
SMN1; SMN2 Q16637 1/20 0.68
APAF1 O14727 1/20 0.67
POLB P06746 1/20 0.67
RECQL P46063 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
HTR2A P28223 3/20 0.66
HTR1A P08908 2/20 0.66
HTR2C P28335 2/20 0.66
SLC6A4 P31645 2/20 0.66
HTR7 P34969 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL1120026 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL289043 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL7327 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL475349 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL4732053 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL23141133 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL289042 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL4732052 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL475350 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL19161120 0.98 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528627-A High-efficiency carbon fixation foliage spray fertilizer 河南河大科技发展有限公司 2025-02-28 CN claimed
CN-109665917-A Suitable for the liquid suspension set meal fertilizer of solanaceous vegetables and its preparation and method of administration 福建省农业科学院土壤肥料研究所 2019-04-23 CN claimed
CN-103768071-B A kind of oral formulations treating diabetes 中国医药工业研究总院 2016-08-17 CN claimed
CN-103768071-A Oral preparation for treating diabetes CHINA STATE INST PHARM IND 2014-05-07 CN claimed
CN-117486778-A Tryptophan zinc chelate and preparation method thereof 长沙兴嘉生物工程股份有限公司 2024-02-02 CN disclosed
CN-103768071-B A kind of oral formulations treating diabetes 中国医药工业研究总院 2016-08-17 CN disclosed
CN-104026520-A Potato cake and preparing method thereof SHANDONG HUACHANG FOOD TECHNOLOGY CO LTD 2014-09-10 CN disclosed
CN-103768071-A Oral preparation for treating diabetes CHINA STATE INST PHARM IND 2014-05-07 CN disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
US-6162442-A Use of aqueous L-Tryptophan and/or L-Threonine salt solutions DEGUSSA-HULS AG (DE) 2000-12-19 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
EP-0371406-B1 OXYALKYLATED QUATERNARY AMMONIUM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID COMPOUNDS DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1993-08-04 EP disclosed
US-5076828-A Immersing seeds into quaternary solution prior to planting DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1991-12-31 US disclosed
EP-0371406-A1 Oxyalkylated quaternary ammonium compounds, processes for production thereof, and plant growth regulating compositions containing said compounds DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1990-06-06 EP disclosed