Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603518 | 0.85 | KDM4E (0.51) | KDM4EHRH3MAOBHRH2HRH1 | |
| Ammonia Solution, Strong SCHEMBL7603171 | 0.84 | KDM4E (0.50) | KDM4EHRH3MAOBHRH2HRH1 | |
| SCHEMBL761884 | 0.83 | KDM4E (0.47) | KDM4EHRH3MAOBHRH2HRH1 | |
| SCHEMBL24233761 | 0.81 | SIGMAR1 (0.51) | KDM4EHRH3 | |
| SCHEMBL3983783 | 0.81 | KDM4E (0.53) | KDM4EHRH3MAOBHRH2HRH1 | |
| SCHEMBL9374424 | 0.80 | HRH3 (0.53) | KDM4EHRH3MAOBHRH2HRH1 | |
| SCHEMBL7771642 | 0.79 | KDM4E (0.47) | KDM4EHRH3MAOBHTR7 | |
| SCHEMBL25844752 | 0.78 | HRH3 (0.49) | KDM4EHRH3MAOBHTR7 | |
| SCHEMBL27360827 | 0.78 | KDM4E (0.49) | KDM4EHRH3MAOBHRH2HRH1 | |
| SCHEMBL7602980 | 0.77 | KDM4E (0.58) | KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092713-A2 | Piperidinopentanamines and their use as catalysts in the preparation of urethanes | LONZA AG (CH) | 2001-04-18 | — | — | EP | claimed |
| US-6080865-A | A POLYMERIZATION CATALYSTS IN THE PRODUCTION OF POLYURETHANES; A REACTION PRODUCT OF THE 2-METHYLGLUTARONITRILE WITH HYDROGEN | LONZA AG (CH) | 2000-06-27 | — | — | US | claimed |
| EP-0822933-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1998-02-11 | — | — | EP | claimed |
| WO-1996033986-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1996-10-31 | — | — | WO | claimed |
| EP-0822933-B1 | PROCESS FOR PRODUCING PIPERIDINOPENTANAMINES | LONZA AG (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-1092713-A2 | Piperidinopentanamines and their use as catalysts in the preparation of urethanes | LONZA AG (CH) | 2001-04-18 | — | — | EP | disclosed |
| US-6080865-A | A POLYMERIZATION CATALYSTS IN THE PRODUCTION OF POLYURETHANES; A REACTION PRODUCT OF THE 2-METHYLGLUTARONITRILE WITH HYDROGEN | LONZA AG (CH) | 2000-06-27 | — | — | US | disclosed |
| EP-0822933-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033986-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1996-10-31 | — | — | WO | disclosed |