Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415579 | 0.75 | CYP2D6 (0.39) | CYP2D6HDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL7782767 | 0.75 | HTR2A (0.34) | GPR3HTR2A | |
| SCHEMBL29724650 | 0.70 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL2210400 | 0.69 | MAOA (0.42) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL8693899 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A | |
| SCHEMBL30990099 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A | |
| SCHEMBL197033 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A | |
| SCHEMBL31297722 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A | |
| SCHEMBL29430337 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A | |
| SCHEMBL8693987 | 0.69 | HTR2A (0.41) | CYP2D6MAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303822-B1 | Aromatic hydroxythiol synthesis using diazonium salts | ALLIEDSIGNAL INC. | 2001-10-16 | — | — | US | disclosed |
| EP-1140816-A1 | AROMATIC HYDROXYTHIOL SYNTHESIS USING DIAZONIUMSALTS | AlliedSignal Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037439-A1 | AROMATIC HYDROXYTHIOL SYNTHESIS USING DIAZONIUM SALTS | ALLIEDSIGNAL INC. (US) | 2000-06-29 | — | — | WO | disclosed |
| US-6054622-A | Aromatic hydroxythiol synthesis using diazonium salts | ALLIEDSIGNAL INC (US) | 2000-04-25 | — | — | US | disclosed |
| US-RE28760-E | Photographic element including superimposed silver halide layers of different speeds | EASTMAN KODAK COMPANY (US) | 1976-04-06 | — | — | US | disclosed |