Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | HRAS | P01112 | 7/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782148 | 1.00 | FNTA (0.37) | FNTAFNTBCYP19A1PGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL8300866 | 0.99 | FNTA (0.37) | FNTAFNTBCYP19A1PGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL8300863 | 0.99 | FNTA (0.37) | FNTAFNTBCYP19A1PGGT1BHRAS | |
| SCHEMBL8620754 | 0.80 | CYP19A1 (0.38) | FNTAFNTBCYP19A1PGGT1BCNR1 | |
| SCHEMBL8080364 | 0.79 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8392309 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL8571106 | 0.73 | HRAS (0.36) | FNTAFNTBHRASCTSLCTSB | |
| SCHEMBL8387631 | 0.72 | BACE1 (0.43) | CTSL | |
| SCHEMBL8387624 | 0.72 | BACE1 (0.43) | CTSL | |
| SCHEMBL7811238 | 0.65 | FNTA (0.37) | FNTAFNTBCYP19A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001518281-A | — | — | 2001-10-16 | — | — | JP | claimed |
| EP-1019530-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-1009854-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1999010524-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | claimed |
| WO-1999010523-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | claimed |
| EP-1009854-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999010523-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |