SCHEMBL7782166 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CAPN1	P07384	16/20	0.58

▸	CTSB	P07858	5/20	0.45

▸	CTSL	P07711	2/20	0.44

▸	F10	P00742	2/20	0.37

▸	CTSS	P25774	2/20	0.37

▸	CTSK	P43235	2/20	0.37

▸	F2	P00734	1/20	0.36

▸	PRSS1	P07477	1/20	0.36

▸	PRSS2	P07478	1/20	0.36

▸	PRSS3	P35030	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7786987	0.88	CAPN1 (0.45)	CAPN1CTSBCTSLF10CTSS
SCHEMBL7787775	0.84	CAPN1 (0.51)	CAPN1CTSB
SCHEMBL7787026	0.82	CAPN1 (0.51)	CAPN1CTSBF10F2PRSS1
SCHEMBL7791341	0.82	CAPN1 (0.61)	CAPN1CTSB
SCHEMBL7782229	0.81	CAPN1 (0.51)	CAPN1CTSBF10F2PRSS1
SCHEMBL7790034	0.77	CAPN1 (0.48)	CAPN1CTSB
SCHEMBL7787794	0.76	CAPN1 (0.53)	CAPN1CTSB
SCHEMBL7787789	0.75	CAPN1 (0.48)	CAPN1CTSB
SCHEMBL7787776	0.75	CAPN1 (1.00)	CAPN1CTSBCTSLCTSSCTSK
SCHEMBL7789890	0.73	CAPN1 (1.00)	CAPN1CTSBCTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6251917-B1	Benzamidoaldehydes and their use as cysteine protease inhibitors	BASF AKTIENGESELLSCHAFT (DE)	2001-06-26	—	—	US	disclosed