SCHEMBL7787775

SCHEMBL7787775

Cc1ccc(-c2ccc3ccccc3c2C(N)=O)cc1C(=O)NC(C=O)Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 12/20 0.51
CTSB P07858 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790079 0.86 ROCK2 (0.43) CAPN1CTSB
SCHEMBL7787026 0.85 CAPN1 (0.51) CAPN1CTSB
SCHEMBL7791341 0.85 CAPN1 (0.61) CAPN1CTSB
SCHEMBL7782166 0.84 CAPN1 (0.58) CAPN1CTSB
SCHEMBL7782229 0.84 CAPN1 (0.51) CAPN1CTSB
SCHEMBL7787794 0.84 CAPN1 (0.53) CAPN1CTSB
SCHEMBL7787789 0.83 CAPN1 (0.48) CAPN1CTSB
SCHEMBL7447782 0.80 CAPN1 (0.57) CAPN1CTSBPOLB
SCHEMBL7790034 0.78 CAPN1 (0.48) CAPN1CTSBPOLB
SCHEMBL7692827 0.75 CTSB (0.41) CAPN1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251917-B1 Benzamidoaldehydes and their use as cysteine protease inhibitors BASF AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed