Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 12/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782194 | 1.00 | CAPN1 (1.00) | CAPN1TBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL7379589 | 0.88 | CAPN1 (1.00) | CAPN1CTSBACE | |
| SCHEMBL7786977 | 0.88 | CAPN1 (1.00) | CAPN1CTSBACE | |
| SCHEMBL7782112 | 0.83 | CAPN1 (0.71) | CAPN1TBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL7782111 | 0.83 | CAPN1 (0.71) | CAPN1TBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL7791324 | 0.81 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7791328 | 0.81 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7313231 | 0.80 | CAPN1 (0.67) | CAPN1CTSLCTSB | |
| SCHEMBL6940473 | 0.80 | CAPN1 (0.67) | CAPN1CTSLCTSB | |
| SCHEMBL7322071 | 0.80 | CAPN1 (0.67) | CAPN1TBXA2RPTGER4PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |