Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 10/20 | 1.00 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791324 | 1.00 | CAPN1 (1.00) | CAPN1KIFC1SGMS2MAOBLMNA | |
| SCHEMBL7790004 | 0.84 | CAPN1 (0.72) | CAPN1KIFC1SGMS2MAOBLMNA | |
| SCHEMBL7790007 | 0.84 | CAPN1 (0.72) | CAPN1KIFC1SGMS2MAOBLMNA | |
| SCHEMBL7789863 | 0.84 | CAPN1 (0.72) | CAPN1MAOBMAPTNPC1ALDH1A1 | |
| SCHEMBL7789862 | 0.84 | CAPN1 (0.72) | CAPN1MAOBMAPTNPC1ALDH1A1 | |
| SCHEMBL7782199 | 0.81 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7782194 | 0.81 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7380711 | 0.79 | CAPN1 (0.67) | CAPN1L3MBTL1GAAALDH1A1HPGD | |
| SCHEMBL7782101 | 0.79 | CAPN1 (0.67) | CAPN1L3MBTL1GAAALDH1A1HPGD | |
| SCHEMBL24863013 | 0.78 | CAPN1 (0.66) | CAPN1LMNAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |