SCHEMBL7782307

SCHEMBL7782307

CCCCC1COC(CCCCC2COC(c3ccc(F)c(F)c3)OC2)OC1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
ALDH1A1 P00352 1/20 0.32
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782303 1.00 HTR2A (0.34) HTR2AHTR2CHTR2BALDH1A1IDO1
SCHEMBL7774556 0.95 HTR2A (0.34) HTR2AHTR2CHTR2BKDM1A
SCHEMBL7774553 0.95 HTR2A (0.34) HTR2AHTR2CHTR2BKDM1A
SCHEMBL7778803 0.94 HTR2A (0.33) HTR2AHTR2CHTR2BALDH1A1KDM1A
SCHEMBL7778797 0.94 HTR2A (0.33) HTR2AHTR2CHTR2BALDH1A1KDM1A
SCHEMBL9150818 0.93 HTR2A (0.35) HTR2AHTR2CHTR2BIDO1TDO2
SCHEMBL7774342 0.93 ALDH1A1 (0.33) HTR2AHTR2CHTR2BALDH1A1KDM1A
SCHEMBL7774335 0.93 ALDH1A1 (0.33) HTR2AHTR2CHTR2BALDH1A1KDM1A
SCHEMBL9785326 0.92 ALDH1A1 (0.35) HTR2AHTR2CHTR2BALDH1A1IDO1
SCHEMBL8997261 0.92 ALDH1A1 (0.35) HTR2AHTR2CHTR2BALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732330-B1 Di-1,3-dioxane derivatives useful as liquid crystals ROLIC AG (CH) 2001-09-12 EP disclosed
US-5667721-A Liquid crystalline di-1,3-dioxane derivatives ROLIC AG (CH) 1997-09-16 US disclosed
EP-0732330-A1 Di-1,3-dioxane derivatives useful as liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1996-09-18 EP disclosed