SCHEMBL7782415

SCHEMBL7782415

CN(CCC#N)CCN(C)CCC#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
HPGD P15428 1/20 0.42
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
LCK P06239 1/20 0.37
TSHR P16473 5/20 0.36
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
LOX P28300 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6608458 0.97 ALDH1A1 (0.44) ALDH1A1HPGDCA12CA2CA3
SCHEMBL16892353 0.88 CHRM2 (0.42) ALDH1A1HPGDCA12CA2CA3
SCHEMBL11668526 0.86
SCHEMBL9797780 0.86 TSHR (0.43) ALDH1A1HPGDCA12CA2CA3
SCHEMBL1219354 0.84
SCHEMBL2478663 0.84
SCHEMBL6655057 0.84
SCHEMBL21280606 0.83 LCK (0.38) ALDH1A1HPGDCA12CA2CA3
SCHEMBL129312 0.82
Hydrochloric Acid SCHEMBL9547197 0.82 ALDH1A1 (0.41) ALDH1A1HPGDTDP1LCKTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190208-A1 ELECTROLESS NICKEL PLATING BATHS COMPRISING AMINONITRILES AND A METHOD FOR DEPOSITION OF NICKEL AND NICKEL ALLOYS ATOTECH Deutschland GmbH (DE) 2017-07-12 EP disclosed
EP-0688314-B1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AG (DE) 2001-10-04 EP disclosed
US-5804559-A WATER SOLUBILITY HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-08 US disclosed
EP-0688314-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed