Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782564 | 0.78 | DAO (0.49) | DAOCDC7DBF4HTR2CHTR2B | |
| SCHEMBL3237564 | 0.73 | TAAR1 (0.64) | DAOHTR2CHTR2BACP3TAAR1 | |
| SCHEMBL30783235 | 0.71 | DAO (0.48) | DAOHTR2CHTR2BACP3TAAR1 | |
| SCHEMBL29738927 | 0.71 | DAO (0.51) | DAOHTR2CHTR2B | |
| Water SCHEMBL29809068 | 0.70 | DAO (0.50) | DAOHTR2CHTR2B | |
| SCHEMBL2741585 | 0.69 | TAAR1 (0.59) | DAOTAAR1 | |
| SCHEMBL28320156 | 0.69 | HTR2C (0.54) | DAOCDC7DBF4HTR2CHTR2B | |
| SCHEMBL30370514 | 0.68 | TAAR1 (0.58) | DAOHTR2CHTR2BACP3TAAR1 | |
| SCHEMBL7435425 | 0.68 | TAAR1 (0.58) | DAOHTR2CHTR2BACP3TAAR1 | |
| SCHEMBL14718571 | 0.68 | DAO (0.53) | DAOHTR2CHTR2BACP3AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-6281219-B1 | 4,6-BIS-ARYL-PYRIMIDINES WHEREIN THE AROMATIC GROUPS ARE ATTACHED VIA TWO LINKING GROUPS WHICH ARE DIFFERENT FROM ONE ANOTHER. | AMERICAN CYANAMID CO. | 2001-08-28 | — | — | US | disclosed |
| EP-0972770-A1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | disclosed |