Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.71 |
| ▸ | CNR1 | P21554 | 9/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777725 | 0.88 | CNR2 (0.71) | CNR2CNR1SLC6A3 | |
| SCHEMBL7782586 | 0.86 | CNR2 (0.74) | CNR2CNR1SLC6A3 | |
| SCHEMBL8060941 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL29388664 | 0.79 | CNR2 (1.00) | CNR2CNR1SLC6A3 | |
| SCHEMBL29988815 | 0.72 | CNR2 (1.00) | CNR2CNR1SLC6A3 | |
| SCHEMBL6331573 | 0.72 | CNR2 (1.00) | CNR2CNR1SLC6A3 | |
| SCHEMBL29388381 | 0.72 | CNR2 (1.00) | CNR2CNR1SLC6A3 | |
| SCHEMBL8071354 | 0.72 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL8061024 | 0.72 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL29988425 | 0.71 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833818-B1 | 3-ACYLINDOLES AS CB2 RECEPTOR AGONISTS | SANOFI SYNTHELABO (FR) | 2001-10-17 | — | — | EP | claimed |
| EP-0833818-A1 | CB 2? RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1998-04-08 | — | — | EP | claimed |
| WO-1997000860-A1 | CB2 RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1997-01-09 | — | — | WO | claimed |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9656981-B2 | Peripherally-acting cannabinoid receptor agonists for chronic pain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-27 | — | — | US | disclosed |
| EP-0833818-B1 | 3-ACYLINDOLES AS CB2 RECEPTOR AGONISTS | SANOFI SYNTHELABO (FR) | 2001-10-17 | — | — | EP | disclosed |
| US-6013648-A | IMMUNOMODULATORS | SANOFI (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0833818-A1 | CB 2? RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000860-A1 | CB2 RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | CNR2 1/4885CNR1 2/4885SLC6A3 999/4885 |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | CNR2 1/4885CNR1 2/4885SLC6A3 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.