Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782853 | 1.00 | ACE (0.35) | ACEECE1PIN1FNTAFNTB | |
| SCHEMBL7780966 | 0.89 | FNTA (0.37) | ACEPIN1FNTAFNTB | |
| SCHEMBL7780968 | 0.89 | FNTA (0.37) | ACEPIN1FNTAFNTB | |
| SCHEMBL6308761 | 0.87 | PIN1 (0.34) | ACEPIN1 | |
| SCHEMBL29893883 | 0.87 | PIN1 (0.34) | ACEPIN1MME | |
| SCHEMBL6308753 | 0.87 | PIN1 (0.34) | ACEPIN1 | |
| SCHEMBL6425164 | 0.86 | PIN1 (0.34) | ACEPIN1 | |
| SCHEMBL4182507 | 0.86 | PIN1 (0.47) | ACEPIN1MME | |
| SCHEMBL1666820 | 0.86 | SLC15A2 (0.42) | PIN1 | |
| SCHEMBL4182503 | 0.86 | PIN1 (0.47) | ACEPIN1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233310-A | Antiarteriosclerotic N-(mercaptoacyl)-histidines | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1980-11-11 | — | — | US | claimed |
| EP-0845505-B1 | Spherical colour pigments, process for their preparation and their use | DMC2 DEGUSSA METALS CATALYSTS (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-6074754-A | MEAN PARTICLE DIAMETER OF LESS THAN 10 MUM, ON THE BASIS OF AN OXIDIC OR SILICATE SUBSTRATE MATERIAL WITH NOBLE METAL DISTRIBUTED EXTREMELY FINELY ON AND/OR IN THE PARTICLES. PREFERRED PIGMENTS ARE PURPLE-COLORED | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0845505-A2 | Spherical colour pigments, process for their preparation and their use | Degussa Aktiengesellschaft (DE) | 1998-06-03 | — | — | EP | disclosed |