SCHEMBL7782852

SCHEMBL7782852

N[C@@H](Cc1c[nH]c(C(=O)CS)n1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
SLC7A5 Q01650 3/20 0.41
CYP3A4 P08684 3/20 0.41
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.38
MAPT P10636 3/20 0.38
BLM P54132 3/20 0.38
PMP22 Q01453 3/20 0.38
KMT2A Q03164 3/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 2/20 0.38
HIF1A Q16665 2/20 0.38
MPO P05164 1/20 0.38
PTGS1 P23219 2/20 0.37
PKM P14618 2/20 0.37
ALPI P09923 1/20 0.37
XIAP P98170 1/20 0.37
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL359889 0.84 CYP1A2 (0.42) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL31370049 0.83 CYP1A2 (0.46) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL25354300 0.79 CYP1A2 (0.43) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL9717852 0.79 CYP1A2 (0.43) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL25354296 0.79 CYP1A2 (0.43) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL9717841 0.79 CYP1A2 (0.43) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL1065159 0.78 SLC7A5 (0.45) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL1065160 0.78 SLC7A5 (0.45) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL25354020 0.78 SLC7A5 (0.44) CYP1A2SLC7A5CYP3A4KDM4ELMNA
SCHEMBL25354014 0.78 SLC7A5 (0.44) CYP1A2SLC7A5CYP3A4KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744245-A POLYMERIC RESIN IN SOLUTION, WATER, COSOLVENT, AND THIOLATE OF PRECIOUS METAL JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1998-04-28 US claimed
EP-0514073-B1 Precious metal composition JOHNSON MATTHEY PLC (GB) 1995-07-05 EP claimed
US-5401535-A Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1995-03-28 US claimed
US-5281635-A Polym,er resin and water-solvent solution of thiolate of platinum, palladium, gold, or silver for forming film on firing JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-01-25 US claimed
EP-0514073-A2 Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1992-11-19 EP claimed
EP-0845505-B1 Spherical colour pigments, process for their preparation and their use DMC2 DEGUSSA METALS CATALYSTS (DE) 2001-10-04 EP disclosed
US-6074754-A MEAN PARTICLE DIAMETER OF LESS THAN 10 MUM, ON THE BASIS OF AN OXIDIC OR SILICATE SUBSTRATE MATERIAL WITH NOBLE METAL DISTRIBUTED EXTREMELY FINELY ON AND/OR IN THE PARTICLES. PREFERRED PIGMENTS ARE PURPLE-COLORED DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-06-13 US disclosed
US-6013798-A WATER-BASED COMPOSITION FOR DECORATING SUBSTRATE, I.E., CERAMIC OR GLASS WITH BRIGHT GOLD FILM UPON FIRING COMPRISING A NON-RADIOACTIVE GOLD THIOLATE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2000-01-11 US disclosed
EP-0845505-A2 Spherical colour pigments, process for their preparation and their use Degussa Aktiengesellschaft (DE) 1998-06-03 EP disclosed
US-5744245-A POLYMERIC RESIN IN SOLUTION, WATER, COSOLVENT, AND THIOLATE OF PRECIOUS METAL JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1998-04-28 US disclosed
EP-0514073-B1 Precious metal composition JOHNSON MATTHEY PLC (GB) 1995-07-05 EP disclosed
US-5401535-A Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1995-03-28 US disclosed
US-5281635-A Polym,er resin and water-solvent solution of thiolate of platinum, palladium, gold, or silver for forming film on firing JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-01-25 US disclosed
EP-0514073-A2 Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1992-11-19 EP disclosed