Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717841 | 1.00 | CYP1A2 (0.43) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL359889 | 0.84 | CYP1A2 (0.42) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL31370049 | 0.83 | CYP1A2 (0.46) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL25354300 | 0.82 | CYP1A2 (0.43) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL25354296 | 0.82 | CYP1A2 (0.43) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL25354014 | 0.81 | SLC7A5 (0.44) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL25354020 | 0.81 | SLC7A5 (0.44) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL31295696 | 0.80 | CYP1A2 (0.41) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL7782852 | 0.79 | CYP1A2 (0.43) | CYP1A2SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL31369922 | 0.79 | SLC7A5 (0.43) | CYP1A2SLC7A5CYP3A4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436611-A4 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | — | 1992-03-11 | — | — | EP | disclosed |
| EP-0436611-A1 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1991-07-17 | — | — | EP | disclosed |
| WO-1990006102-A1 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | PEPTIDE TECHNOLOGY LIMITED (AU) | 1990-06-14 | — | — | WO | disclosed |