SCHEMBL7782923

SCHEMBL7782923

COC(=O)OC(C)CC(C)(C)OOC(=O)C(=O)OC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.35
CTSK P43235 1/20 0.31
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SCN1A P35498 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
NAAA Q02083 1/20 0.31
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSH P09668 1/20 0.30
CYP19A1 P11511 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331492 0.91 EPHX1 (0.35) EPHX1CTSKHTTLMNACYP1A2
SCHEMBL7792497 0.84 EPHX1 (0.33) EPHX1HTTSMN1; SMN2NAAACYP19A1
SCHEMBL7788674 0.83 EPHX1 (0.36) EPHX1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL7790600 0.79 APOBEC3A (0.40) HTTNPC1RAB9ASMN1; SMN2CYP19A1
SCHEMBL7931090 0.78 EPHX1 (0.41) EPHX1HTTCYP1A2NPC1RAB9A
SCHEMBL7782915 0.74 HTT (0.37) EPHX1CTSKHTTSMN1; SMN2NAAA
SCHEMBL7753339 0.73 EPHX1 (0.37) EPHX1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL9101612 0.73 EPHX1 (0.37) EPHX1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL7757456 0.72 EPHX1 (0.34) EPHX1HTTNAAACYP19A1
SCHEMBL11423685 0.70 CTSK (0.41) EPHX1CTSKCTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed