SCHEMBL7783030

SCHEMBL7783030

CC(O)CC(C)(C)OOC(=O)C(=O)OC1CCC(C(C)(C)C)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
HTT P42858 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 2/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
GAA P10253 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LIPA P38571 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7757438 0.88 CYP19A1 (0.41) CYP19A1APOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL7790600 0.87 APOBEC3A (0.40) CYP19A1APOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL7788674 0.86 EPHX1 (0.36) CYP19A1SMN1; SMN2HTTNPC1RAB9A
SCHEMBL8530822 0.84 APOBEC3A (0.43) CYP19A1APOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL7931085 0.76 MAPT (0.41) CYP19A1APOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL7753339 0.73 EPHX1 (0.37) CYP19A1SMN1; SMN2HTTKDM4ENPC1
SCHEMBL9101612 0.73 EPHX1 (0.37) CYP19A1SMN1; SMN2HTTKDM4ENPC1
SCHEMBL7782918 0.73 MMP8 (0.36) TSHRNPSR1
SCHEMBL8331492 0.73 EPHX1 (0.35) CYP19A1SMN1; SMN2HTTKDM4ENPC1
SCHEMBL7783000 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed