Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776286 | 1.00 | ACE2 (0.47) | ACE2LMNATSHRADH1BADH1C | |
| SCHEMBL5686363 | 1.00 | ACE2 (0.47) | ACE2LMNATSHRADH1BADH1C | |
| SCHEMBL1441507 | 0.97 | LMNA (0.43) | ACE2LMNATSHRADH1BADH1C | |
| SCHEMBL28896926 | 0.90 | ACE2 (0.57) | ACE2LMNATSHRADH1BADH1C | |
| SCHEMBL7776283 | 0.90 | ACE2 (0.52) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL7781562 | 0.90 | ACE2 (0.52) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL7782859 | 0.90 | ACE2 (0.52) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL497221 | 0.90 | — | — | |
| SCHEMBL234630 | 0.88 | TSHR (0.39) | ACE2LMNATSHROPRM1CA1 | |
| SCHEMBL978906 | 0.87 | ACE2 (0.48) | ACE2LMNATSHRADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137737-A1 | LIQUID CRYSTAL COMPOUND | Rolic AG (CH) | 2001-10-04 | — | — | EP | claimed |
| WO-2000031211-A1 | LIQUID CRYSTAL COMPOUND | ROLIC AG (CH) | 2000-06-02 | — | — | WO | claimed |