SCHEMBL7783164

SCHEMBL7783164

C=CC(=O)N[SiH]1CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169893 0.82 TSHR (0.31) TSHR
SCHEMBL9422208 0.79 GAA (0.36) TSHRALDH1A1
SCHEMBL543024 0.75
SCHEMBL16754901 0.73
SCHEMBL8857957 0.71
SCHEMBL2142068 0.70
SCHEMBL4257894 0.69
SCHEMBL16499595 0.68
SCHEMBL1190603 0.67
SCHEMBL2355549 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915482-B1 Improved X-ray intensifying screen EASTMAN KODAK CO (US) 2001-10-10 EP disclosed
EP-0421643-B1 Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING & MFG (US) 2000-12-27 EP disclosed
US-6162553-A X-ray intensifying screen EASTMAN KODAK COMPANY (US) 2000-12-19 US disclosed
EP-0915482-A1 Improved X-ray intensifying screen Imation Corp. (US) 1999-05-12 EP disclosed
CN-1215419-A Free-radically polymerizable compositions capable of being applied with electrostatic assistance MINNESOTA MINING & MFG (US) 1999-04-28 CN disclosed
EP-0576544-B1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1997-06-04 EP disclosed
EP-0576579-B1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES MINNESOTA MINING & MFG (US) 1995-11-15 EP disclosed
EP-0404324-B1 Acrylamidoaryloxy functional silicon compounds DOW CORNING (US) 1994-10-26 EP disclosed
EP-0583259-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING. MINNESOTA MINING & MFG (US) 1994-02-23 EP disclosed
EP-0576579-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
EP-0576544-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
US-5264278-A Low temperature adhesion, shock resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-23 US disclosed
WO-1992016590-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016593-A2 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016591-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
EP-0421643-A2 Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-04-10 EP disclosed
EP-0404324-A1 Acrylamidoaryloxy functional silicon compounds DOW CORNING CORPORATION (US) 1990-12-27 EP disclosed