Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 5/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781447 | 0.87 | TNKS (0.48) | TNKSTNKS2PIM1PIM2PARP1 | |
| SCHEMBL7782100 | 0.87 | PARP1 (0.47) | TNKSTNKS2PIM1PIM2PARP1 | |
| SCHEMBL7776880 | 0.87 | RAB9A (0.52) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7776892 | 0.81 | TNKS (0.48) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7783507 | 0.80 | PARP1 (0.47) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7783529 | 0.77 | TNKS (0.49) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7776864 | 0.76 | TNKS (0.48) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7776849 | 0.76 | PARP1 (0.51) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7776883 | 0.72 | PARP1 (0.60) | TNKSTNKS2PARP1PARP3PARP15 | |
| SCHEMBL7776800 | 0.71 | PARP1 (0.47) | TNKSTNKS2PARP1PARP3PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |