Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783351 | 1.00 | CYP11B1 (0.40) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7788491 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP11B2MIFGRIN2DGRIN3B | |
| SCHEMBL7788488 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP11B2MIFGRIN2DGRIN3B | |
| SCHEMBL8148142 | 0.87 | GRIN2D (0.45) | ALDH1A1RELAMIFGRIN2DGRIN3B | |
| SCHEMBL8148138 | 0.87 | GRIN2D (0.45) | ALDH1A1RELAMIFGRIN2DGRIN3B | |
| SCHEMBL7792278 | 0.86 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1GRIN2D | |
| SCHEMBL7792274 | 0.86 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1GRIN2D | |
| SCHEMBL8604005 | 0.83 | NPC1 (0.55) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8154205 | 0.83 | NPC1 (0.55) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7791484 | 0.77 | MAPT (0.44) | MIFGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |