Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604005 | 1.00 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7789065 | 0.83 | KIF11 (0.41) | NPC1RAB9ASMN1; SMN2KIF11NPFFR1 | |
| SCHEMBL7789066 | 0.83 | KIF11 (0.41) | NPC1RAB9ASMN1; SMN2KIF11NPFFR1 | |
| SCHEMBL7788488 | 0.83 | CYP11B1 (0.50) | CYP11B1CYP11B2KIF11NFE2L2GRIN2D | |
| SCHEMBL7788491 | 0.83 | CYP11B1 (0.50) | CYP11B1CYP11B2KIF11NFE2L2GRIN2D | |
| SCHEMBL7783351 | 0.83 | CYP11B1 (0.40) | NPC1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7783349 | 0.83 | CYP11B1 (0.40) | NPC1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7793351 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7793357 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792488 | 0.81 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |