Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783362 | 1.00 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2TUBB1TUBB4A | |
| SCHEMBL7788650 | 0.87 | GRIN2D (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7788649 | 0.87 | GRIN2D (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7792278 | 0.86 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TUBB1TUBB4A | |
| SCHEMBL7792274 | 0.86 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TUBB1TUBB4A | |
| SCHEMBL7792437 | 0.83 | TUBB1 (0.48) | NPC1RAB9ASMN1; SMN2TUBB1ALDH1A1 | |
| SCHEMBL7793484 | 0.83 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7793485 | 0.83 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792440 | 0.83 | TUBB1 (0.48) | NPC1RAB9ASMN1; SMN2TUBB1ALDH1A1 | |
| SCHEMBL7792161 | 0.82 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2TUBB1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |