Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783487 | 1.00 | TAAR1 (0.46) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7792626 | 0.90 | GRIN2D (0.56) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7792630 | 0.90 | GRIN2D (0.56) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7791264 | 0.89 | GRIN2D (0.51) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7791261 | 0.89 | GRIN2D (0.51) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7788701 | 0.88 | GRIN2D (0.50) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7788705 | 0.88 | GRIN2D (0.50) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7791265 | 0.86 | LMNA (0.41) | TAAR1GRIN1GRIN2BLMNAALDH1A1 | |
| SCHEMBL7791260 | 0.86 | LMNA (0.41) | TAAR1GRIN1GRIN2BLMNAALDH1A1 | |
| SCHEMBL7793578 | 0.86 | TAAR1 (0.37) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |