Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.70 |
| ▸ | TNKS | O95271 | 8/20 | 0.70 |
| ▸ | PARP1 | P09874 | 5/20 | 0.70 |
| ▸ | WNT3A | P56704 | 5/20 | 0.70 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.70 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.70 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.70 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.70 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.70 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | MTHFD2 | P13995 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776852 | 0.87 | TNKS2 (0.73) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL7782072 | 0.86 | TNKS2 (0.71) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27436932 | 0.86 | TNKS2 (0.71) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL7783531 | 0.85 | TNKS (0.60) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27436124 | 0.85 | TNKS2 (0.70) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27445179 | 0.85 | TNKS2 (0.70) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL25782527 | 0.83 | TNKS2 (0.70) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27436612 | 0.83 | TNKS2 (0.67) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27435351 | 0.83 | TNKS2 (0.67) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL7783488 | 0.83 | TNKS2 (1.00) | TNKS2TNKSPARP1WNT3APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |