SCHEMBL7783608

SCHEMBL7783608

CCCc1ccc2c(c1)C(C)C(=O)O2

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
GAA P10253 1/20 0.35
MGLL Q99685 1/20 0.33
LYPLA1 O75608 1/20 0.33
LYPLA2 O95372 1/20 0.33
ABHD16A O95870 1/20 0.33
MTNR1A P48039 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
CA2 P00918 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
IAPP P10997 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8981476 0.91 SKP2 (0.38) LYPLA1LYPLA2ABHD16AGPR84CA2
SCHEMBL7785798 0.87 BRD4 (0.40) GAANPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL7785526 0.74 GAA (0.58) GAAALDH1A1
SCHEMBL7783606 0.73 BRD4 (0.43) MGLLNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL17797155 0.73 ALDH1A1 (0.47) GAAALDH1A1
SCHEMBL7783609 0.72 HDAC4 (0.39) GAANPC1ALDH1A1RAB9A
SCHEMBL7783996 0.72 MAPK1 (0.42) CNR2GAANPC1ALDH1A1RAB9A
SCHEMBL7785869 0.70 GAA (0.36) GAACA2ALDH1A1SMN1; SMN2
SCHEMBL7783242 0.70 ALDH1A1 (0.48) GAACA2NPC1ALDH1A1RAB9A
SCHEMBL7785861 0.70 ALDH1A1 (0.48) GAANPC1ALDH1A1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP claimed
US-5679634-A Use of dihydrobenzofuranones as perfuming ingredients FIRMENICH S.A. (CH) 1997-10-21 US claimed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP claimed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO claimed
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP disclosed
US-5679634-A Use of dihydrobenzofuranones as perfuming ingredients FIRMENICH S.A. (CH) 1997-10-21 US disclosed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP disclosed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO disclosed