Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577287 | 0.83 | PNMT (0.43) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL648530 | 0.79 | PNMT (0.44) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7716985 | 0.78 | PNMT (0.46) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7641126 | 0.78 | PNMT (0.46) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL3119422 | 0.77 | PNMT (0.42) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL5351418 | 0.77 | PNMT (0.42) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL5836874 | 0.77 | NPC1 (0.48) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL6557465 | 0.76 | PNMT (0.47) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7641521 | 0.75 | PNMT (0.44) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL9226145 | 0.75 | PNMT (0.44) | PNMTNPC1RAB9AHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604908-B1 | Process for the polymerisation of alpha-olefins using metallocene compounds having ligands of fluorenylic type | BASELL TECHNOLOGY CO BV (NL) | 2001-09-19 | — | — | EP | disclosed |
| EP-0604908-A2 | Metallocene compounds having ligands of fluorenylic type | Montell Technology Company bv (NL) | 1994-07-06 | — | — | EP | disclosed |