Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GMNN | O75496 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605861 | 0.97 | FAAH (0.44) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL8979251 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL31482280 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL11800657 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL4949246 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL25805874 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL11800775 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL11804172 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL11803719 | 0.95 | FAAH (0.49) | FAAHCNR1CNR2MAPK1MAPT | |
| SCHEMBL27884281 | 0.93 | FAAH (0.46) | FAAHCNR1CNR2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251946-B1 | SATURATED OR UNSATURATED BRANCHED FATTY ACID CONTAINING LIPID ESTER OR FATTY ACID AMIDE TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS, INCLUDING EPILEPSY, MIGRAINES, CHRONIC PAIN AND BIPOLAR DISORDERS | D-PHARM LTD. (IL) | 2001-06-26 | — | — | US | disclosed |