Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518915 | 0.78 | MAPT (0.46) | DAOMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL15564287 | 0.74 | DAO (0.51) | DAOTAAR1IDO1TDO2PTGS1 | |
| SCHEMBL15564051 | 0.72 | DAO (0.57) | DAOARALDH1A1HPGDTAAR1 | |
| SCHEMBL16968259 | 0.71 | DAO (0.56) | DAOARALDH1A1HPGDTAAR1 | |
| SCHEMBL5906372 | 0.69 | — | — | |
| SCHEMBL7783590 | 0.69 | DAO (0.40) | DAOTAAR1 | |
| SCHEMBL7783554 | 0.68 | DAO (0.52) | DAOTAAR1HSD17B10 | |
| SCHEMBL16963974 | 0.68 | P2RX7 (0.33) | ALDH1A1IDO1TDO2MAPT | |
| SCHEMBL7979610 | 0.68 | VHL (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5905968 | 0.67 | IDO1 (0.49) | DAOALDH1A1HPGDIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144392-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040568-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-07-13 | — | — | WO | disclosed |