Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31242450 | 0.84 | FFAR1 (0.42) | TSHRPARP1 | |
| SCHEMBL29021155 | 0.80 | DRD2 (0.30) | — | |
| SCHEMBL871294 | 0.80 | TSHR (0.55) | TSHRPARP1GSTO1 | |
| SCHEMBL610892 | 0.77 | TSHR (0.54) | TSHRPARP1KDM1A | |
| SCHEMBL29364885 | 0.77 | TSHR (0.54) | TSHRPARP1KDM1A | |
| SCHEMBL19661648 | 0.75 | KCNH2 (0.35) | TSHRMAPT | |
| SCHEMBL83447 | 0.74 | TSHR (0.56) | TSHRMAPTKDM1A | |
| SCHEMBL916179 | 0.74 | TSHR (0.56) | TSHRMAPTKDM1A | |
| SCHEMBL7783873 | 0.72 | TSHR (0.36) | TSHR | |
| SCHEMBL3564666 | 0.72 | CCNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-4754047-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4522822-A | Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals | AMERICAN CYANAMID COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4501751-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0026298-B1 | METHOD FOR PROMOTING GROWTH AND REDUCING FAT IN ANIMALS USING PHENYLETHANOLAMINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1984-04-18 | — | — | EP | disclosed |
| US-4407819-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4404222-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0026298-A1 | Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives | AMERICAN CYANAMID COMPANY (US) | 1981-04-08 | — | — | EP | disclosed |