Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336489 | 0.85 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL29468108 | 0.84 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9615813 | 0.83 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7646645 | 0.83 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL25514 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10314657 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18134826 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8636795 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12701599 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4602612 | 0.80 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885408-B1 | A SCREEN PRINTING STENCIL | SERICOL LTD (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-5994033-A | GRAFT POLYMER | SERICOL LIMITED (GB) | 1999-11-30 | — | — | US | disclosed |