Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336598 | 0.91 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7784243 | 0.85 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL30149349 | 0.78 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28904798 | 0.77 | TSHR (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9615813 | 0.76 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9340405 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL9336567 | 0.74 | — | — | |
| SCHEMBL28441836 | 0.74 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL29468108 | 0.74 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL25514 | 0.73 | TSHR (1.00) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283824-B1 | Polysaccharide graft polymers containing acetal groups and their conversion to aldehyde groups | NAT STARCH CHEM INVEST (US) | 1994-06-08 | — | — | EP | claimed |
| US-5049634-A | Derivatized and/or crosslinked products from acetal- and aldehyde-containing polysaccharide graft polymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-09-17 | — | — | US | claimed |
| US-4866151-A | Polysaccharide graft polymers containing acetal groups and their conversion to aldehyde groups | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-09-12 | — | — | US | claimed |
| EP-0283824-A2 | Polysaccharide graft polymers containing acetal groups and their conversion to aldehyde groups | National Starch and Chemical Investment Holding Corporation (US) | 1988-09-28 | — | — | EP | claimed |
| US-5049634-A | Derivatized and/or crosslinked products from acetal- and aldehyde-containing polysaccharide graft polymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |