Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121711 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2BSLC6A4OPRL1 | |
| SCHEMBL12303672 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2BSLC6A4OPRL1 | |
| SCHEMBL1583058 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL4311675 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL4311498 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL29439088 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL29595508 | 0.79 | HTR2A (0.49) | HTR2AHTR2CHTR2BSLC6A4OPRL1 | |
| SCHEMBL3336712 | 0.78 | SLC6A4 (0.50) | HTR2AHTR2CHTR2BSLC6A4OPRL1 | |
| SCHEMBL11288420 | 0.78 | HSD11B1 (0.39) | HTR2AHTR2CHTR2BSLC6A4HPGD | |
| SCHEMBL15159990 | 0.77 | SLC6A2 (0.47) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |