Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784290 | 1.00 | MEN1 (0.33) | MEN1KMT2ATHRBLMNATTR | |
| SCHEMBL7784278 | 0.79 | HDAC3 (0.30) | — | |
| SCHEMBL7784274 | 0.79 | HDAC3 (0.30) | — | |
| SCHEMBL4351803 | 0.74 | LMNA (0.49) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL131676 | 0.74 | LMNA (0.49) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL5023080 | 0.72 | ATM (0.50) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8656427 | 0.71 | TSHR (0.42) | MEN1KMT2ATHRBLMNATTR | |
| SCHEMBL2763358 | 0.71 | MAPT (0.33) | ALDH1A1MAPTUSP2ALOX15KDM4E | |
| SCHEMBL7875447 | 0.71 | TSHR (0.41) | MEN1KMT2ALMNATTRMAPT | |
| SCHEMBL5050873 | 0.71 | MAPT (0.33) | ALDH1A1MAPTUSP2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | claimed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | claimed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | claimed |
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | disclosed |