Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31717937 | 1.00 | PIK3CD (0.41) | PIK3CDKHKBACE1IDO1POLB | |
| SCHEMBL2947783 | 0.83 | PIK3CD (0.41) | PIK3CDKHKBACE1POLBGLA | |
| SCHEMBL7786072 | 0.82 | MPL (0.35) | PIK3CDBACE1IDO1POLBGLA | |
| SCHEMBL9967097 | 0.82 | KHK (0.50) | PIK3CDKHKBACE1POLBGLA | |
| SCHEMBL29687228 | 0.80 | PIK3CD (0.37) | PIK3CDIDO1CASP3XPO1ADRB2 | |
| SCHEMBL675996 | 0.80 | PIK3CD (0.37) | PIK3CDIDO1CASP3XPO1ADRB2 | |
| SCHEMBL11276391 | 0.80 | PIK3CD (0.39) | PIK3CDKHKBACE1POLBGLA | |
| SCHEMBL10853416 | 0.77 | PIK3CD (0.40) | PIK3CDBACE1XPO1ADRB2MPL | |
| SCHEMBL1420767 | 0.77 | PIK3CD (0.42) | PIK3CDBACE1POLBGLAGAA | |
| SCHEMBL21670482 | 0.77 | NOTUM (0.35) | PIK3CDIDO1CASP3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574439-A | Method for preparing 2-amino-3 chloro-5-trifluoromethylpyridine | 山东汇盟生物科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-109963851-B | Fused bicyclic pyridine compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111574439-A | Method for preparing 2-amino-3 chloro-5-trifluoromethylpyridine | 山东汇盟生物科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | disclosed |
| EP-1140489-A1 | MULTILAYER STRUCTURES | THE DOW CHEMICAL COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000024577-A1 | MULTILAYER STRUCTURES | THE DOW CHEMICAL COMPANY (US) | 2000-05-04 | — | — | WO | disclosed |
| US-5849920-A | Substituted trifluoromethylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0596491-B1 | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5491239-A | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0596491-A1 | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4349681-A | 2-Amino-3-chloro-5-trifluoromethylpyridine | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1982-09-14 | — | — | US | disclosed |
| EP-0031218-A1 | A 2-amino-trifluoromethyl-halogenopyridine compound and a process for producing the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-07-01 | — | — | EP | disclosed |