Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.36 |
| ▸ | XPO1 | O14980 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687228 | 1.00 | PIK3CD (0.37) | PIK3CDNOTUMXPO1CYP11B1CYP11B2 | |
| SCHEMBL20360347 | 0.92 | PIK3CD (0.33) | PIK3CDNOTUMXPO1CYP11B1CYP11B2 | |
| SCHEMBL10853416 | 0.87 | PIK3CD (0.40) | PIK3CDNOTUMXPO1CYP11B1CYP11B2 | |
| SCHEMBL20350717 | 0.84 | — | — | |
| SCHEMBL10746403 | 0.84 | XPO1 (0.31) | NOTUMXPO1 | |
| SCHEMBL28454953 | 0.82 | NOTUM (0.35) | PIK3CDNOTUMCYP11B1CYP11B2CASP3 | |
| SCHEMBL21670482 | 0.82 | NOTUM (0.35) | PIK3CDNOTUMXPO1CYP11B1CYP11B2 | |
| SCHEMBL30285322 | 0.82 | NOTUM (0.35) | PIK3CDNOTUMXPO1CYP11B1CYP11B2 | |
| SCHEMBL31717937 | 0.80 | PIK3CD (0.41) | PIK3CDNOTUMXPO1ADRB2CASP3 | |
| SCHEMBL7784302 | 0.80 | PIK3CD (0.41) | PIK3CDNOTUMXPO1ADRB2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717095-A | Method for preparing 2-chloro-3-trifluoromethylpyridine and 2-chloro-5-trifluoromethylpyridine | 山东汇盟生物科技股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-112441966-A | Method for producing 2-chloro-3-trifluoromethylpyridine from 2,3, 6-trichloro-5-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-03-05 | — | — | CN | claimed |
| CN-112159350-A | Preparation method of 2-chloro-3-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-01-01 | — | — | CN | claimed |
| CN-111574439-A | Method for preparing 2-amino-3 chloro-5-trifluoromethylpyridine | 山东汇盟生物科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| US-20180194728-A1 | METHOD FOR PREPARING PENTACHLOROPYRIDINE BY UTIILIZING DCTF RECTIFYING SHORT STEAMING RESIDUES | YANCHENG INSTITUTE OF TECHNOLOGY | 2018-07-12 | — | — | US | claimed |
| US-10017473-B1 | Method for preparing pentachloropyridine by utilizing DCTF rectifying short steaming residues | YANCHENG INST TECH (CN) | 2018-07-10 | — | — | US | claimed |
| EP-0078410-B1 | PROCESS FOR PRODUCING 3-CHLORO-5-TRIFLUOROMETHYLPYRIDINES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-05-27 | — | — | EP | claimed |
| US-4490534-A | CHLORINATION IN VAPOR PHASE, PRESENCE OF CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-12-25 | — | — | US | claimed |
| US-4420618-A | CHLORINATION, METAL CHLORIDE CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-12-13 | — | — | US | claimed |
| EP-0078410-A2 | Process for producing 3-chloro-5-trifluoromethylpyridines | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-05-11 | — | — | EP | claimed |
| CN-117263854-A | Preparation method of 2,5, 6-trichloronicotinic acid | 山东友聚医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-110475764-B | Method for purifying trifluoromethylpyridines | 石原产业株式会社 | 2023-03-31 | — | — | CN | disclosed |
| CN-115784977-A | Synthesis process of 2-chloro-3-trifluoromethylpyridine | 淄博新农基作物科学有限公司 | 2023-03-14 | — | — | CN | disclosed |
| EP-3608309-B1 | METHOD FOR PURIFYING TRIFLUOROMETHYLPYRIDINE COMPOUND | ISHIHARA SANGYO KAISHA (JP) | 2022-07-13 | — | — | EP | disclosed |
| CN-114292227-A | Method for preparing 2-chloro-3-trifluoromethylpyridine | 大连九信精细化工有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-4490534-A | CHLORINATION IN VAPOR PHASE, PRESENCE OF CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-12-25 | — | — | US | disclosed |
| US-4420618-A | CHLORINATION, METAL CHLORIDE CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| US-4420618-A | CHLORINATION, METAL CHLORIDE CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0092117-A1 | Process for producing chloronicotinic acid compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| EP-0078410-A2 | Process for producing 3-chloro-5-trifluoromethylpyridines | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-05-11 | — | — | EP | disclosed |