Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL3647974 | 1.00 | THRB (0.43) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL7779801 | 1.00 | THRB (0.43) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL7784344 | 1.00 | THRB (0.43) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL8329107 | 0.98 | THRB (0.47) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL2985292 | 0.98 | THRB (0.47) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL8440905 | 0.93 | THRB (0.39) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL19551091 | 0.91 | THRB (0.55) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL7218279 | 0.89 | TSHR (0.40) | THRBTSHRALDH1A1CES2 | |
| Methacrylic Acid SCHEMBL7212837 | 0.89 | TSHR (0.40) | THRBTSHRALDH1A1HSD17B10CES2 | |
| Methacrylic Acid SCHEMBL7219056 | 0.88 | TSHR (0.43) | THRBTSHRALDH1A1HSD17B10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141094-A1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M Espe AG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042092-A1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2000-07-20 | — | — | WO | disclosed |