Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786278 | 0.86 | GRM5 (0.33) | KDM4ENPSR1HPGDALDH1A1PPARG | |
| SCHEMBL678557 | 0.78 | KMT2A (0.41) | KDM4ENPSR1HPGDALDH1A1PPARG | |
| Chlorfenapyr SCHEMBL28402415 | 0.75 | RXFP1 (0.32) | KDM4ENPSR1HPGDALDH1A1PPARG | |
| Chlorfenapyr SCHEMBL40337 | 0.75 | RXFP1 (0.35) | KDM4EHPGDALDH1A1RXFP1GRIA2 | |
| SCHEMBL7782866 | 0.74 | NPSR1 (0.35) | KDM4ENPSR1HPGDALDH1A1PPARG | |
| Chlorfenapyr SCHEMBL27488880 | 0.74 | RXFP1 (0.35) | KDM4EHPGDALDH1A1RXFP1GRIA2 | |
| Chlorfenapyr SCHEMBL28530561 | 0.74 | RXFP1 (0.35) | KDM4EHPGDALDH1A1RXFP1GRIA2 | |
| Chlorfenapyr SCHEMBL28508419 | 0.73 | RXFP1 (0.36) | KDM4EHPGDALDH1A1RXFP1GRIA2 | |
| SCHEMBL9567374 | 0.73 | RXFP1 (0.34) | KDM4EHPGDALDH1A1RXFP1GRIA2 | |
| SCHEMBL7782871 | 0.72 | ALDH1A1 (0.38) | KDM4EHPGDALDH1A1PPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |