SCHEMBL7784530

SCHEMBL7784530

COC(=O)NNC(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
GLA P06280 1/20 0.46
GAA P10253 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
STAT3 P40763 1/20 0.43
PKM P14618 1/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11650232 0.89 GLA (0.41) ALDH1A1GLAGAATDP1LMNA
SCHEMBL8396318 0.87
SCHEMBL15688514 0.87
SCHEMBL10360714 0.87
SCHEMBL10779290 0.84
SCHEMBL10876978 0.84
SCHEMBL3625397 0.82
SCHEMBL24514107 0.80 APLNR (0.50) ALDH1A1GAATDP1LMNAMEN1
SCHEMBL19508782 0.80 TSHR (0.43) ALDH1A1GLAGAATDP1LMNA
SCHEMBL11101832 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US claimed
CN-108264493-B Process for preparing oxydiazacyclic compound and application thereof 泸州东方农化有限公司 2022-09-30 CN disclosed
EP-3564219-B1 PROCESS FOR PREPARING OXADIAZACYCLO COMPOUND AND USE THEREOF ORIENTAL LUZHOU AGROCHEMICALS CO LTD (CN) 2021-02-24 EP disclosed
EP-3564219-A1 PROCESS FOR PREPARING OXADIAZACYCLO COMPOUND AND USE THEREOF Oriental (Luzhou) Agrochemicals. Co., Ltd. (CN) 2019-11-06 EP disclosed
WO-2012085501-A1 8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG PHARMINOX LIMITED (GB) 2012-06-28 WO disclosed
WO-2011107726-A1 METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF 4-OXO-3,4-DIHYDRO-IMIDAZO[5,1-D][1,2,3,5]TETRAZINES PHARMINOX LTD (GB) 2011-09-09 WO disclosed
EP-0840717-B1 PREPARATION OF ALDEHYDES OR KETONES FROM ALCOHOLS SYNGENTA LTD (GB) 2001-10-24 EP disclosed
EP-0986531-A1 CATALYTIC OXIDATIVE PROCESS FOR PREPARING CARBOXYLIC ACIDS FROM ALCOHOLS OR ALDEHYDES ZENECA LIMITED (GB) 2000-03-22 EP disclosed
US-5912388-A IN THE PRESENCE OF A BASE, A CATALYTIC AMOUNT OF A COPPER SALT AND A SUITABLE LIGNAD UNDER ANHYDROUS CONDITIONS. ZENECA LIMITED (GB) 1999-06-15 US disclosed
WO-1998051654-A1 CATALYTIC OXIDATIVE PROCESS FOR PREPARING CARBOXYLIC ACIDS FROM ALCOHOLS OR ALDEHYDES ZENECA LIMITED (GB) 1998-11-19 WO disclosed
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5380828-A Stabilization by being grafted onto a polymer CIBA-GEIGY CORPORATION (US) 1995-01-10 US disclosed