Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637903 | 0.81 | CYP2D6 (0.38) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL4436955 | 0.80 | TSHR (0.47) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL132574 | 0.78 | LMNA (0.39) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL3690415 | 0.78 | LMNA (0.43) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL8682114 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL3394794 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL1147850 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL1147732 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL4875812 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN | |
| SCHEMBL1147869 | 0.77 | LMNA (0.42) | CYP2D6LMNAMAPTSPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252060-B1 | COMPLEX CONTAINING DIDEOXYGUANOSINE | NEXSTAR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | claimed |