Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546966 | 0.83 | MAPK14 (0.44) | CYP1A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7782884 | 0.72 | MAPT (0.39) | RHEBCYP1A2PDE7APDE7BTUBB4A | |
| SCHEMBL10922675 | 0.71 | CYP1A2 (0.50) | CYP1A2PDE7APDE7BCHRNA7CYP2C9 | |
| SCHEMBL8665030 | 0.70 | IKBKB (0.32) | RHEBCYP1A2LMNAL3MBTL1 | |
| SCHEMBL18561707 | 0.70 | CHRNA7 (0.64) | CYP1A2PDE7APDE7BCHRNA7CYP2C9 | |
| SCHEMBL1931122 | 0.70 | CHRNA7 (0.64) | CYP1A2PDE7APDE7BCHRNA7CYP2C9 | |
| SCHEMBL10534271 | 0.69 | CYP1A2 (0.71) | CYP1A2CHRNA7CYP2C9MEN1KMT2A | |
| Biphenyl SCHEMBL17985318 | 0.67 | CYP1A2 (0.61) | CYP1A2CHRNA7CYP2C9MEN1KMT2A | |
| SCHEMBL3784717 | 0.66 | PDE7A (0.59) | RHEBPDE7APDE7BCHRNA7CYP2C9 | |
| SCHEMBL29242030 | 0.66 | SLC6A4 (0.47) | RHEBCYP1A2CHRNA7CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |