Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784864 | 0.93 | MEN1 (0.42) | MAPTSMN1; SMN2NPSR1XBP1HTT | |
| SCHEMBL7778163 | 0.82 | CHEK2 (0.36) | MAPTKDM4EMAPK14GCGRRHEB | |
| SCHEMBL7783637 | 0.81 | PDE7A (0.47) | MAPTSMN1; SMN2NPSR1HTTPDE7A | |
| SCHEMBL8664038 | 0.79 | KDM4E (0.34) | MAPTNPSR1XBP1HTTKDM4E | |
| SCHEMBL7782851 | 0.73 | TUBB4A (0.40) | MAPTSMN1; SMN2NPSR1XBP1HTT | |
| SCHEMBL7784751 | 0.72 | RHEB (0.47) | KDM4EMAPK14GCGRPDE7APDE7B | |
| SCHEMBL8798565 | 0.72 | KDM4E (0.43) | MAPTSMN1; SMN2NPSR1HTTKDM4E | |
| SCHEMBL9015117 | 0.72 | GCGR (0.50) | MAPTNPSR1HTTKDM4EMAPK14 | |
| SCHEMBL7782969 | 0.71 | TUBB4A (0.39) | MAPTSMN1; SMN2NPSR1XBP1HTT | |
| SCHEMBL29172448 | 0.70 | GCGR (0.38) | MAPTNPSR1XBP1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |