Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449281 | 0.95 | EPHX2 (0.49) | EPHX2PPARATRPV1 | |
| SCHEMBL8449285 | 0.95 | EPHX2 (0.49) | EPHX2PPARATRPV1 | |
| SCHEMBL7764267 | 0.89 | PPARA (0.50) | EPHX2CNR2PPARATRPV1CNR1 | |
| SCHEMBL11560956 | 0.89 | MEN1 (0.50) | EPHX2CNR2TRPV1CNR1ALDH1A1 | |
| Diethanolamine SCHEMBL11560953 | 0.86 | MEN1 (0.53) | EPHX2CNR2TRPV1CNR1ALDH1A1 | |
| Diethanolamine SCHEMBL11560966 | 0.86 | MEN1 (0.53) | EPHX2CNR2TRPV1CNR1ALDH1A1 | |
| Sulfuric Acid SCHEMBL8750920 | 0.85 | MEN1 (0.52) | EPHX2ALDH1A1MEN1MAPTKMT2A | |
| Oleyl Sulfate SCHEMBL432676 | 0.84 | CNR2 (0.48) | EPHX2CNR2PPARATRPV1CNR1 | |
| Oleyl Sulfate SCHEMBL432673 | 0.84 | CNR2 (0.48) | EPHX2CNR2PPARATRPV1CNR1 | |
| SCHEMBL22814028 | 0.82 | EPHX2 (0.50) | EPHX2PPARATRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1145708-A2 | Cosmetic and use thereof | KAO CORPORATION (JP) | 2001-10-17 | — | — | EP | disclosed |