Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990209 | 0.91 | ALDH1A1 (0.48) | PPARAALDH1A1 | |
| SCHEMBL7784997 | 0.89 | EPHX2 (0.45) | PPARACNR2EPHX2CNR1ALDH1A1 | |
| SCHEMBL359429 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL7999840 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL7999843 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL19032668 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL8459195 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL19032670 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL359431 | 0.87 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL20564617 | 0.86 | PPARA (0.43) | PPARACNR2EPHX2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102836-A1 | WATER-IN-OIL MICROEMULSION FOR PROVIDING COSMETIC ATTRIBUTES TO FABRIC SOFTENING BASE COMPOSITION | Colgate-Palmolive Company (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006690-A1 | WATER-IN-OIL MICROEMULSION FOR PROVIDING COSMETIC ATTRIBUTES TO FABRIC SOFTENING BASE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |